Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Involved in cellular glucose homeostasis; protein import into nucleus; and regulation of glucokinase activity. Localizes to nucleus. Is expressed in diencephalon lateral wall mantle layer; liver left lobe; liver right lobe; and midbrain mantle layer. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (glucokinase regulator).