Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Involved in filopodium assembly; nervous system development; and regulation of cell migration. Located in several cellular components, including phagocytic vesicle; postsynaptic density; and postsynaptic membrane. Is active in dendritic spine. Is expressed in several structures, including brain; eye; future spinal cord; heart; and spinal cord. Orthologous to several human genes including SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2).