Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable calcium ion binding activity. Predicted to be involved in negative regulation of coagulation and positive regulation of phagocytosis. Predicted to act upstream of or within blood coagulation and fibrinolysis. Located in extracellular space. Is expressed in several structures, including brain; frenulum; liver; and tooth. Human ortholog(s) of this gene implicated in autosomal dominant thrombophilia due to protein S deficiency; autosomal recessive thrombophilia due to protein S deficiency; cerebral infarction; and protein S deficiency. Orthologous to human PROS1 (protein S).