Automated description from the Alliance of Genome Resources (Release 7.0.0)
A structural constituent of nuclear pore. Acts upstream of or within mRNA export from nucleus; protein import into nucleus; and regulation of cell cycle. Predicted to be located in cytoplasmic side of nuclear pore. Predicted to be part of nuclear pore. Is expressed in future spinal cord; lung; and nervous system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Orthologous to human NUP214 (nucleoporin 214).