Automated description from the Alliance of Genome Resources
A structural constituent of nuclear pore. Involved in mRNA export from nucleus; protein import into nucleus; and regulation of cell cycle. Predicted to localize to the cytoplasmic side of nuclear pore. Human ortholog(s) of this gene implicated in acute myeloid leukemia; brain disease; and precursor lymphoblastic lymphoma/leukemia. Is expressed in future spinal cord; lung; and nervous system. Orthologous to human NUP214 (nucleoporin 214).