Automated description from the Alliance of Genome Resources (Release 3.2)
A structural constituent of nuclear pore. Involved in mRNA export from nucleus; protein import into nucleus; and regulation of cell cycle. Predicted to localize to cytoplasmic side of nuclear pore. Is expressed in future spinal cord; lung; and nervous system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; and brain disease. Orthologous to human NUP214 (nucleoporin 214).