Automated description from the Alliance of Genome Resources
Exhibits BMP receptor activity. Involved in several processes, including circulatory system development; negative regulation of cell proliferation involved in heart valve morphogenesis; and regulation of transcription by RNA polymerase II. Localizes to the cell surface; plasma membrane; and postsynaptic density. Used to study primary pulmonary hypertension. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).