Automated description from the Alliance of Genome Resources
Exhibits store-operated calcium channel activity. Involved in positive regulation of cytosolic calcium ion concentration. Localizes to the plasma membrane and slit diaphragm. Used to study focal segmental glomerulosclerosis 2. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Is expressed in several structures, including cochlea; genitourinary system; gut; liver lobe; and nervous system. Orthologous to human TRPC6 (transient receptor potential cation channel subfamily C member 6).