Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables identical protein binding activity. Predicted to be involved in several processes, including negative regulation of interleukin-2 production; opsonization; and regulation of phagocytosis. Predicted to act upstream of or within innate immune response and respiratory gaseous exchange by respiratory system. Located in cytoplasm. Is expressed in epidermis spinous layer; lung; lung surfactant; otic capsule; and skeleton. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to human SFTPD (surfactant protein D).