Automated description from the Alliance of Genome Resources
Exhibits high voltage-gated calcium channel activity and voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels. Involved in several processes, including cellular ion homeostasis; chemical synaptic transmission; and nervous system development. Localizes to several cellular components, including the glutamatergic synapse; neuronal cell body; and voltage-gated calcium channel complex. Used to study Lambert-Eaton myasthenic syndrome; brain disease (multiple); and hereditary ataxia (multiple). Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 42; hereditary ataxia (multiple); and migraine (multiple). Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and trigeminal nerve. Orthologous to human CACNA1A (calcium voltage-gated channel subunit alpha1 A).