Automated description from the Alliance of Genome Resources
Exhibits activin receptor binding activity. Involved in several processes, including animal organ development; digestive tract morphogenesis; and nodal signaling pathway. Predicted to localize to the cell surface and extracellular region. Used to study dextro-looped transposition of the great arteries 1; double outlet right ventricle; right atrial isomerism; and visceral heterotaxy. Human ortholog(s) of this gene implicated in visceral heterotaxy. Is expressed in several structures, including embryo mesoderm; intermediate mesenchyme; neural ectoderm; and primitive streak. Orthologous to several human genes including CFC1B (cripto, FRL-1, cryptic family 1B).