Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits uracil DNA N-glycosylase activity. Involved in isotype switching and somatic hypermutation of immunoglobulin genes. Localizes to mitochondrion and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; olfactory epithelium; and vibrissa. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Orthologous to human UNG (uracil DNA glycosylase).