Automated description from the Alliance of Genome Resources
Exhibits uracil DNA N-glycosylase activity. Involved in isotype switching and somatic hypermutation of immunoglobulin genes. Localizes to the mitochondrion and nucleus. Human ortholog(s) of this gene implicated in dysgammaglobulinemia and immunodeficiency with hyper IgM type 5. Is expressed in several structures, including alimentary system; brain; genitourinary system; olfactory epithelium; and vibrissa. Orthologous to human UNG (uracil DNA glycosylase).