Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to have several functions, including gamma-tubulin binding activity; histone acetyltransferase activity; and protein C-terminus binding activity. Involved in several processes, including DNA metabolic process; gamete generation; and signal transduction by p53 class mediator. Localizes to chromosome; cytoplasm; and nucleus. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and hemolymphoid system gland. Used to study Fanconi anemia complementation group D1 and breast cancer. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple); brain cancer (multiple); hereditary breast ovarian cancer syndrome; melanoma (multiple); and reproductive organ cancer (multiple). Orthologous to human BRCA2 (BRCA2 DNA repair associated).
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