Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits several functions, including LIM domain binding activity; ion channel binding activity; and thyroid hormone receptor coactivator activity. Involved in several processes, including cardiac muscle cell development; positive regulation of transport; and protein localization to plasma membrane. Localizes to Z disc. Predicted to colocalize with cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including alimentary system; heart; limb; musculature; and trunk somite. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy and dilated cardiomyopathy 1AA. Orthologous to human ACTN2 (actinin alpha 2).