Automated description from the Alliance of Genome Resources
Exhibits several functions, including LIM domain binding activity; ion channel binding activity; and thyroid hormone receptor coactivator activity. Involved in several processes, including cardiac muscle cell development; positive regulation of transport; and protein localization to plasma membrane. Localizes to the Z disc. Predicted to colocalize with the cortical actin cytoskeleton and plasma membrane. Human ortholog(s) of this gene implicated in arrhythmogenic right ventricular cardiomyopathy and dilated cardiomyopathy 1AA. Is expressed in several structures, including alimentary system; heart; limb; musculature; and trunk somite. Orthologous to human ACTN2 (actinin alpha 2).