Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits ATPase activity; actin binding activity; and microtubule binding activity. Involved in several processes, including posttranslational protein targeting to endoplasmic reticulum membrane; regulation of focal adhesion assembly; and regulation of neuron projection arborization. Localizes to cytoplasm; cytoskeleton; and postsynaptic density. Predicted to colocalize with intermediate filament. Is expressed in several structures, including central nervous system; genitourinary system; limb segment; lung; and skeletal musculature. Human ortholog(s) of this gene implicated in lissencephaly. Orthologous to human MACF1 (microtubule actin crosslinking factor 1).