Automated description from the Alliance of Genome Resources
Exhibits ATPase activity; actin binding activity; and microtubule binding activity. Involved in several processes, including positive regulation of Wnt signaling pathway; posttranslational protein targeting to endoplasmic reticulum membrane; and regulation of focal adhesion assembly. Localizes to the cytoplasm; cytoskeleton; and postsynaptic density. Predicted to colocalize with the intermediate filament. Human ortholog(s) of this gene implicated in lissencephaly. Orthologous to human MACF1 (microtubule actin crosslinking factor 1).