Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits mitogen-activated protein kinase binding activity. Involved in negative regulation of osteoblast differentiation; regulation of bone mineralization; and regulation of stress-activated MAPK cascade. Localizes to late endosome and phagophore assembly site. Colocalizes with autophagosome. Is expressed in central nervous system; genitourinary system; heart; and retina. Orthologous to human NBR1 (NBR1 autophagy cargo receptor).