Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including embryonic limb morphogenesis; embryonic skeletal system morphogenesis; and roof of mouth development. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study parietal foramina. Human ortholog(s) of this gene implicated in craniosynostosis and parietal foramina. Orthologous to human ALX4 (ALX homeobox 4).