Automated description from the Alliance of Genome Resources
Contributes to serine C-palmitoyltransferase activity. Involved in adipose tissue development and sphingolipid biosynthetic process. Localizes to the mitochondrion. Used to study psoriasis. Human ortholog(s) of this gene implicated in hereditary sensory and autonomic neuropathy type 1C. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human SPTLC2 (serine palmitoyltransferase long chain base subunit 2).