Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein homodimerization activity; and tau protein binding activity. Predicted to contribute to DNA binding activity. Involved in several processes, including animal organ development; embryonic morphogenesis; and transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to the cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in Lynch syndrome; cervical cancer; and ovarian cancer. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Orthologous to human SMAD2 (SMAD family member 2).