Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; intestinal epithelial cell development; and negative regulation of chondrocyte differentiation. Predicted to localize to nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human NKX3-2 (NK3 homeobox 2).