Automated description from the Alliance of Genome Resources
Exhibits cytokine activity. Involved in several processes, including T-helper 1 cell cytokine production; lipid homeostasis; and positive regulation of cell differentiation. Localizes to the extracellular space. Used to study atopic dermatitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; allergic rhinitis; biliary atresia; hepatitis B; and vasculitis (multiple). Is expressed in several structures, including back skin; colon; dorsal aorta; lymphatic system; and reproductive system. Orthologous to human IL18 (interleukin 18).