Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including collagen binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and fibronectin binding activity. Involved in proteolysis involved in protein catabolic process and thyroid hormone generation. Acts upstream of or within bone resorption; collagen catabolic process; and negative regulation of cartilage development. Located in external side of plasma membrane; extracellular space; and lysosome. Is expressed in several structures, including bone; central nervous system; connective tissue; gut; and sensory organ. Human ortholog(s) of this gene implicated in pycnodysostosis. Orthologous to human CTSK (cathepsin K).