Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including heart development; negative regulation of cell fate specification; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including cardioblast migration; mesodermal cell migration; and signal transduction involved in regulation of gene expression. Located in nucleus. Is expressed in several structures, including allantois; central nervous system; embryo mesenchyme; primitive streak; and sensory organ. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human MESP1 (mesoderm posterior bHLH transcription factor 1).