Automated description from the Alliance of Genome Resources
Exhibits aspartic-type endopeptidase activity; cyclin-dependent protein serine/threonine kinase inhibitor activity; and cysteine-type endopeptidase activity involved in execution phase of apoptosis. Involved in several processes, including anterior neural tube closure; lymphocyte homeostasis; and negative regulation of lymphocyte proliferation. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in Parkinson's disease; colon cancer; and lung non-small cell carcinoma. Is expressed in several structures, including gut; heart; limb; nervous system; and respiratory system. Orthologous to human CASP3 (caspase 3).