Automated description from the Alliance of Genome Resources
Predicted to have several functions, including ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light chain binding activity. Involved in several processes, including animal organ development; cilium organization; and positive regulation of smoothened signaling pathway. Localizes to the apical part of cell; axoneme; and motile cilium. Used to study VACTERL association and asphyxiating thoracic dystrophy 3. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 3. Orthologous to human DYNC2H1 (dynein cytoplasmic 2 heavy chain 1).