Automated description from the Alliance of Genome Resources (Release 3.0)
Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in several processes, including animal organ development; cilium organization; and positive regulation of smoothened signaling pathway. Localizes to apical part of cell; axoneme; and motile cilium. Used to study VACTERL association and asphyxiating thoracic dystrophy 3. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 3. Is expressed in brain ventricular layer and olfactory epithelium. Orthologous to human DYNC2H1 (dynein cytoplasmic 2 heavy chain 1).