Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have ATP-dependent microtubule motor activity, minus-end-directed; dynein intermediate chain binding activity; and dynein light intermediate chain binding activity. Involved in cilium movement involved in cell motility; epithelial cilium movement involved in extracellular fluid movement; and flagellated sperm motility. Localizes to sperm flagellum. Is expressed in cerebellum; choroid plexus; and lateral ventricle choroid plexus. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 37 and spermatogenic failure 18. Orthologous to human DNAH1 (dynein axonemal heavy chain 1).