Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables type I interferon binding activity and type I interferon receptor activity. Involved in several processes, including cellular response to interferon-alpha; defense response to symbiont; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within T cell activation; positive regulation of cytokine production; and regulation of peptidyl-tyrosine phosphorylation. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in hepatitis C and primary immunodeficiency disease. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1).