Automated description from the Alliance of Genome Resources (Release 8.3.0)
Predicted to enable voltage-gated sodium channel activity. Involved in circadian rhythm; detection of mechanical stimulus involved in sensory perception; and detection of temperature stimulus involved in sensory perception of pain. Acts upstream of or within several processes, including behavioral response to pain; inflammatory response; and response to toxic substance. Predicted to be located in axon terminus; node of Ranvier; and plasma membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in axon. Is expressed in several structures, including brain; gut; immune system; male reproductive gland or organ; and respiratory system epithelium. Human ortholog(s) of this gene implicated in erythromelalgia and paroxysmal extreme pain disorder. Orthologous to human SCN9A (sodium voltage-gated channel alpha subunit 9).
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