Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables semaphorin receptor binding activity. Involved in several processes, including cardiac endothelial to mesenchymal transition; outflow tract septum morphogenesis; and positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis. Acts upstream of or within several processes, including chordate embryonic development; circulatory system development; and dichotomous subdivision of terminal units involved in salivary gland branching. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SEMA3C (semaphorin 3C).