Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; beta-catenin binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including digestive tract morphogenesis; endodermal cell fate specification; and heart morphogenesis. Acts upstream of or within several processes, including circulatory system development; embryonic morphogenesis; and regulation of gene expression. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; early conceptus; and genitourinary system. Used to study biliary atresia. Human ortholog(s) of this gene implicated in intracranial aneurysm; patent ductus arteriosus; and vesicoureteral reflux. Orthologous to human SOX17 (SRY-box transcription factor 17).