Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; transcription coactivator activity; and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including circulatory system development; embryonic morphogenesis; and negative regulation of Wnt signaling pathway. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; embryo endoderm; and genitourinary system. Used to study biliary atresia. Human ortholog(s) of this gene implicated in vesicoureteral reflux. Orthologous to human SOX17 (SRY-box transcription factor 17).