Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables nodal binding activity. Involved in several processes, including negative regulation of nodal receptor complex assembly; negative regulation of nodal signaling pathway; and negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including anterior/posterior axis specification; cell migration involved in gastrulation; and response to retinoic acid. Located in extracellular region. Is expressed in several structures, including blastocyst; embryo mesoderm; gonad; neural ectoderm; and primitive streak. Orthologous to human LEFTY1 (left-right determination factor 1).