Automated description from the Alliance of Genome Resources
Exhibits calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Involved in several processes, including calcineurin-NFAT signaling cascade; regulation of RNA metabolic process; and regulation of muscle adaptation. Localizes to several cellular components, including the Schaffer collateral - CA1 synapse; calcineurin complex; and cytoplasm. Predicted to colocalize with the cytoplasmic side of plasma membrane and slit diaphragm. Used to study dilated cardiomyopathy. Human ortholog(s) of this gene implicated in infantile or early childhood epileptic encephalopathy 1. Orthologous to human PPP3CA (protein phosphatase 3 catalytic subunit alpha).