Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables guanylate cyclase activity. Acts upstream of or within cGMP biosynthetic process; regulation of cell population proliferation; and response to toxic substance. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in plasma membrane. Is expressed in alimentary system; liver; and spinal cord. Used to study abdominal obesity-metabolic syndrome and obesity. Human ortholog(s) of this gene implicated in congenital diarrhea 6. Orthologous to human GUCY2C (guanylate cyclase 2C).