Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and chromatin DNA binding activity. Involved in several processes, including nervous system development; regulation of transcription, DNA-templated; and visual perception. Localizes to the cytoplasm and nucleus. Used to study holoprosencephaly 5 and schizophrenia. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 5. Orthologous to human ZIC2 (Zic family member 2).