Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables vitamin-K-epoxide reductase (warfarin-sensitive) activity. Involved in blood coagulation and bone development. Acts upstream of or within positive regulation of coagulation and vitamin K metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in chondrocranium; extraembryonic component; jaw; and liver. Human ortholog(s) of this gene implicated in combined deficiency of vitamin K-dependent clotting factors 2 and warfarin resistance. Orthologous to human VKORC1 (vitamin K epoxide reductase complex subunit 1).