Automated description from the Alliance of Genome Resources (Release 5.2.2)
Enables alpha-tubulin binding activity and ubiquitin-protein transferase activity. Involved in regulation of cell cycle. Acts upstream of or within acrosome reaction. Located in acrosomal vesicle. Is expressed in extraembryonic component; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in anencephaly. Orthologous to human TRIM36 (tripartite motif containing 36).