Automated description from the Alliance of Genome Resources (Release 3.0)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including lens development in camera-type eye; negative regulation of skeletal muscle satellite cell proliferation; and regulation of transcription, DNA-templated. Localizes to nucleus. Human ortholog(s) of this gene implicated in branchiootorenal syndrome 2. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and integumental system. Orthologous to human SIX5 (SIX homeobox 5).