Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits identical protein binding activity; protein N-terminus binding activity; and rRNA binding activity. Involved in several processes, including positive regulation of nitrogen compound metabolic process; regulation of gene expression; and ribosome biogenesis. Localizes to several cellular components, including centrosome; nuclear lumen; and ribosomal subunit. Is expressed in several structures, including central nervous system; early conceptus; oocyte; and small intestine crypt of lieberkuhn. Used to study myelodysplastic syndrome. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human NPM1 (nucleophosmin 1).