Automated description from the Alliance of Genome Resources
Exhibits endothelin receptor activity. Involved in several processes, including adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; circulatory system development; and neural crest cell development. Predicted to colocalize with the membrane raft. Used to study mandibulofacial dysostosis with alopecia and velocardiofacial syndrome. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A).