Automated description from the Alliance of Genome Resources
Exhibits ATPase activity, coupled; phosphatidylserine binding activity; and unfolded protein binding activity. Involved in several processes, including chaperone cofactor-dependent protein refolding; late endosomal microautophagy; and positive regulation by host of viral genome replication. Localizes to several cellular components, including the extracellular exosome; glycinergic synapse; and photoreceptor ribbon synapse. Human ortholog(s) of this gene implicated in Parkinson's disease and renal hypertension. Is expressed in several structures, including 1st branchial arch mandibular component; alimentary system; early conceptus; eye; and liver. Orthologous to human HSPA8 (heat shock protein family A (Hsp70) member 8).