Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables integrin binding activity. Involved in postsynapse organization. Acts upstream of or within several processes, including hair follicle development; morphogenesis of an epithelium; and trunk neural crest cell migration. Located in extracellular matrix. Part of laminin-10 complex. Is active in several cellular components, including collagen-containing extracellular matrix; glutamatergic synapse; and synaptic cleft. Is expressed in several structures, including alimentary system; embryo ectoderm; genitourinary system; salivary gland primordium; and sensory organ. Used to study cystic kidney disease. Human ortholog(s) of this gene implicated in familial nephrotic syndrome. Orthologous to human LAMA5 (laminin subunit alpha 5).