Automated description from the Alliance of Genome Resources
Exhibits cyclin binding activity; heparin binding activity; and patched binding activity. Involved in several processes, including animal organ development; chordate embryonic development; and limb morphogenesis. Localizes to the cilium; midbody; and plasma membrane. Predicted to colocalize with the Golgi apparatus. Used to study basal cell carcinoma; medulloblastoma; and nevoid basal cell carcinoma syndrome. Human ortholog(s) of this gene implicated in basal cell carcinoma; holoprosencephaly; holoprosencephaly 7; and nevoid basal cell carcinoma syndrome. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; limb; and urinary system. Orthologous to human PTCH1 (patched 1).