Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to have cytokine receptor activity. Involved in several processes, including defense response to protozoan; positive regulation of gene expression; and regulation of leukocyte activation. Predicted to localize to several cellular components, including centriolar satellite; extracellular space; and nucleoplasm. Is expressed in several structures, including adrenal medulla; early conceptus; hemolymphoid system; medulla oblongata basal plate mantle layer; and reproductive system. Used to study asthma. Human ortholog(s) of this gene implicated in several diseases, including acne; allergic conjunctivitis; autoimmune disease (multiple); human immunodeficiency virus infectious disease; and renal tuberculosis. Orthologous to human IL4R (interleukin 4 receptor).