Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits voltage-gated chloride channel activity. Involved in cell differentiation involved in salivary gland development and retina development in camera-type eye. Predicted to localize to dendrite; integral component of plasma membrane; and perikaryon. Is expressed in several structures, including central nervous system; gonad; hindlimb phalanx; notochord; and visual system. Used to study leukodystrophy. Human ortholog(s) of this gene implicated in idiopathic generalized epilepsy 11 and primary hyperaldosteronism. Orthologous to human CLCN2 (chloride voltage-gated channel 2).