Automated description from the Alliance of Genome Resources (Release 5.2.0)
Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within response to cytokine and response to peptide hormone. Predicted to be located in cytoplasm and nucleus. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in chronic obstructive pulmonary disease; cystic fibrosis; and vasculitis. Orthologous to human SERPINA3 (serpin family A member 3).