Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including E-box binding activity; aryl hydrocarbon receptor binding activity; and protein dimerization activity. Involved in several processes, including cellular response to organic cyclic compound; lymphocyte homeostasis; and regulation of gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II; positive regulation of RNA polymerase II transcription preinitiation complex assembly; and prostate gland development. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; lung; nervous system; and sensory organ. Used to study congenital nystagmus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 85. Orthologous to human AHR (aryl hydrocarbon receptor).