Automated description from the Alliance of Genome Resources
Exhibits oxysterol 7-alpha-hydroxylase activity. Involved in several processes, including B cell chemotaxis; bile acid biosynthetic process; and negative regulation of intracellular estrogen receptor signaling pathway. Predicted to localize to the intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and sensory organ. Orthologous to human CYP7B1 (cytochrome P450 family 7 subfamily B member 1).