Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription factor activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and protein homodimerization activity. Involved in several processes, including detection of mechanical stimulus involved in sensory perception of sound; generation of neurons; and regulation of gene expression. Localizes to the cytosol; nucleus; and transcriptional repressor complex. Predicted to colocalize with the histone methyltransferase complex. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 27; gingival fibromatosis 5; and nephroblastoma. Orthologous to human REST (RE1 silencing transcription factor).