Automated description from the Alliance of Genome Resources (Release 5.3.0)
Predicted to enable ATPase binding activity. Predicted to be involved in cellular iron ion homeostasis; cellular response to increased oxygen levels; and vacuolar acidification. Predicted to act upstream of or within ion transport. Located in acrosomal vesicle and perinuclear region of cytoplasm. Part of ATPase complex; proton-transporting V-type ATPase, V0 domain; and transmembrane transporter complex. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; integumental system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIA and wrinkly skin syndrome. Orthologous to human ATP6V0A2 (ATPase H+ transporting V0 subunit a2).