Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable several functions, including identical protein binding activity; molecular condensate scaffold activity; and nucleic acid binding activity. Acts upstream of or within alternative mRNA splicing, via spliceosome. Located in nucleus. Is active in synapse. Is expressed in several structures, including 1-cell stage embryo; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 20; distal myopathy 3; inclusion body myopathy with early-onset Paget disease of bone with or without frontotemporal dementia 3; and tropical spastic paraparesis. Orthologous to several human genes including HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1 like 2).