Automated description from the Alliance of Genome Resources
Exhibits pre-mRNA intronic binding activity. Involved in negative regulation of mRNA splicing, via spliceosome and negative regulation of transcription by RNA polymerase II. Localizes to the nucleus. Human ortholog(s) of this gene implicated in inclusion body myopathy with Paget disease of bone and frontotemporal dementia. Is expressed in telencephalon. Orthologous to human HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1).