Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to have actin filament binding activity; identical protein binding activity; and nucleoside-triphosphatase activity. Involved in several processes, including inner ear development; modulation of chemical synaptic transmission; and organic substance transport. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; cochlear hair cell ribbon synapse; and postsynaptic actin cytoskeleton. Predicted to colocalize with clathrin-coated endocytic vesicle. Is expressed in inner ear. Used to study autosomal dominant nonsyndromic deafness 22 and autosomal recessive nonsyndromic deafness 37. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 22; autosomal recessive nonsyndromic deafness 37; ovarian cancer; and sensorineural hearing loss. Orthologous to human MYO6 (myosin VI).